Molecular Classification of Eucalyptus camaldulensis and Mentha pulegium Oils Components


  • Francisco Torrens Zaragozá Institut Universitari de Ciència Molecular. Universitat de València.



periodic table, periodic property, periodic law, periodic classification, information entropy


Eucalyptus and Mentha remain flavours in agro-food manufacturing. Oils and components present antifungal potency vs. decay of fruits; E. camaldulensis is led by 1,8-cineole and a?pinene, unlike M. pulegium, which is led by pulegone. The antifungal activity of M. pulegium is three times more frequent than that of E. camaldulensis. The phytochemicals present synergy. Categorization is recommended on the basis of information entropy. The quantity of C-C double bonds, O-atoms and cycles cluster structures. The procedure undergoes a combinatorial upsurge. Nevertheless, following equipartition conjecture, one gets a criterion for selection. Entropy allows clustering phytochemicals according to cluster and principal component analyses. In the periodic classification, components in the same column show similar features. Phytochemicals in the same row present utmost similarity.


Download data is not yet available.


Zhang CQ, Liu YH, Zhu GN. Detection and characterization of benzimidazole resistance on Botrytis cinerea in greenhouse vegetables. Eur J Plant Pathol. 2010;126:509-15.

Moleyar V, Narasimhan P. Antifungal activity of some essential oil components. Food Microbiol. 1986;3:331-6.

Soliman KM, Badeaa RI. Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi. Food Chem Toxicol. 2002;40:1669-75.

Jacet Dongmo PM, Tatsadjieu LN, Tchinda Sonwa E, Kuate J, Amvam Zollo PH, Menut C. Essential oils of Citrus aurantifolia from Cameroon and their antifungal activity against Phaeoramularia angolensis. African J Agric Res. 2009;4:354-8.

Bourkhiss M, Hnach M, Bourkhiss B, Ouhssine M, Chaouch A. Composition chimique et propriétés antimicrobiennes de l’huile essentielle extraite des feuilles de Tetraclinis articulata (Vahl) du Maroc. Afrique Sci. 2007;3:232-42.

Magina MDA, Dalmarco EM, Wisniewski A, Simionatto EL, Dalmarco JB, Pizzolatti MG, Brighente IMC. Chemical composition and antibacterial activity of essential oils of Eugenia species. J Nat Med. 2009;63:345-50.

Bouzouita N, Kachouri F, Ben Halima M, Chaabouni MM. Composition chimique et activités antioxydante, antimicrobienne et insecticide de l’huile essentielle de Juniperus phoenicea. J Soc Chim Tunis. 2008;10:119-25.

Erler F, Ulug I, Yalcinkaya, B. Repellent activity of five essential oils against Culex pipiens. Fitoterapia. 2006;77:491-4.

Tang GW, Yang CJ, Xie LD. Extraction of Trigonella foenum-gracum L. by supercritical fluid CO2 and its contact toxicity to Rhyzopertha dominica (Fabricius) (Coleoptera: Bostrichidae). J Pest Sci. 2007;80:151-7.

Cheng S, Huang C, Chen Y, Yu J, Chen W, Chang S. Chemical compositions and larvicidal activities of leaf essential oils from two eucalyptus species. Bioresour Technol. 2009;100:452-6.

Bhaskara Reddy MV, Angers P, Gosselin A, Arul J. Characterization and use of essential oil from Thymus vulgaris against Botrytis cinerea and Rhizopus stolonifer in strawberry fruits. Phytochemistry. 1997;47:1515-20.

Nielsen PV, Rios R. Inhibition of fungal growth on bread by volatile components from species and herbs and the possible application in active packaging, with special emphasis on mustard essential oil. Int J Food Microbiol. 2000;60:219-29.

Tzortzakis NG. Maintaining postharvest quality of fresh produce with volatile compounds. Innovat Food Sci Emerg Technol. 2006;8:111-6.

Amarti F, Satrani, B, Ghanmi M, Farah A, Aafi A, Aarab L, El Ajjouri M, Chaouch A. Composition chimique et activité antimicrobienne des huiles essetieles de Thymus algeriensis Boiss. and Reut et Thymus ciliatus (Desf) Benth. du Maroc. Biotechnol Agron Soc Environ. 2010;14:141-8.

Bachir Raho G, Benali M. Antibacterial activity of leaf essential oils of Eucalyptus globulus and Eucalyptus comaldulensis. African J Pharm Pharmacol. 2008;2:211-5.

Batish DR, Singh HP, Kohli RK, Kaur S. Eucalyptus essential oil as a natural pesticide. For Ecol Manage. 2008;256:2166-74.

Mahboubi M, Haghi G. Antimicrobial activity and chemical composition of Mentha pulegium L. essential oil. J Ethnopharmacol. 2008;119:325-7.

Snoussi M, Hajlaoui H, Noumi E, Usai D, Sechi LA, Zanetti S, Bakhrouf A. In vitro anti‑vibrio spp. activity and chemical composition of some Tunisian plants. World J Microbiol Biotechnol. 2008;24:3071-6.

Ouraini D, Agoumi A, Ismaili-Alaoui M, Alaoui K, Cherrah Y, Alaoui MA, Belabbas MA. Activité antifongique de l’acide oléique et des huiles essentielles de Thymus saturejoides L. et Mentha pulegium L., comparée aux antifongiques dans les dermatoses mycosiques. Phytotothérapie, 2007;1:6-14.

Hajlaoui H, Trabelsi N, Noumi E, Snoussi M, Fallah H, Ksouri R, Bakhrouf A. Biological activities of the essential oils and methanol extract of two cultivated mint species (Mentha longifolia and Mentha pulegium) used in the Tunisian folkloric medicine. World J Microbiol Biotechnol. 2009;25:2227-38.

Verdeguer M, Blazquez MA, Boira H. Phytotoxic effects of Lantana camara, Eucalyptus comaldulensis and Eriocephalus africanus essential oils in weeds of Mediterranean summer crops. Biochem Syst Ecol. 2009;37:362-9.

Akin M, Aktumsek A, Nostro A. Antibacterial activity and composition of the essential oils of Eucalyptus comaldulensis Dehn. and Myrtus communis L. growing in Northern Cyprus. African J Biotechnol. 2010;9:531-5.

Hmiri S, Rahouti M, Habib Z, Satrani B, Ghanmi M, El Ajjouri M. Évaluation du potentiel antifongique des huiles essentielles de Mentha pulegium et d’Eucalyptus camaldulensis dans la lutte biologique contre les champignons responsables de la détérioration des pommes en conservation. Bull Soc R Sci Liège. 2011;80:824-36.

Baser KHC, Buchbauer G, editors. Handbook of essential oils: Science, technology, and applications. Boca Raton (FL): Taylor and Francis; 2010.

Lang G, Buchbauer G. A review on recent research results (2008-2010) on essential oils as antimicrobials and antifungals. A review. Flavour Fragrance J. 2012;27:13-39.

Ibáñez Jaime MD, Blázquez Ferrer MA. Post‑emergent herbicidal activity of Eucalyptus globulus Labill. essential oil. Nereis. 2018;2018(10):25-36.

Ibáñez MD, Blázquez MA. Essential oils: Quality indicators of spices in supermarkets. Nereis. 2019;2019(11):39-50.

Ibáñez MD, Blázquez, MA. Phytotoxic effects of commercial Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris essential oils on weeds, crops, and invasive species. Molecules. 2019;24:2847–1-15.

Varmuza K. Pattern recognition in chemistry. New York: Springer; 1980.

Benzecri JP. L’analyse des données. Paris: Dunod; 1984. Vol. 1.

Tondeur D, Kvaalen E. Equipartition of entropy production. An optimality criterion for transfer and separation processes. Ind Eng Chem Fundam. 1987;26:50-6.

Castellano G, Tena J, Torrens, F. Classification of polyphenolic compounds by chemical structural indicators and its relation to antioxidant properties of Posidonia oceanica (L.) Delile. MATCH Commun Math Comput Chem. 2012;67:231-50.

Castellano G, González-Santander JL, Lara A, Torrens F. Classification of flavonoid compounds by using entropy of information theory. Phytochemistry. 2013;93:182-91.

Torrens F, Castellano G. From Asia to Mediterranean: Soya bean, Spanish legumes and commercial soya bean principal component, cluster and meta-analyses. J Nutr Food Sci. 2014;4(5):98-8.

Castellano G, Lara A, Torrens F. Classification of stilbenoid compounds by entropy of artificial intelligence. Phytochemistry. 2014;97:62-9.

Castellano G, Torrens F. Information entropy-based classification of triterpenoids and steroids from Ganoderma. Phytochemistry. 2015;116:305-13.

Castellano G, Torrens F. Quantitative structure–antioxidant activity models of isoflavonoids: A theoretical study. Int J Mol Sci. 2015;16:12891-906.

Castellano G, Redondo L, Torrens F. QSAR of natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression. Curr Top Med Chem. 2017;17:3256-68.

Torrens F, Castellano G. Structure-activity relationships of cytotoxic lactones as inhibitors and mechanisms of action. Curr Drug Discov Technol. 2020;17:166-182.

Torrens F, Redondo L, Castellano G. Artemisinin: Tentative mechanism of action and resistance. Pharmaceuticals, 2017;10:20-4-4.

Kaufmann A. Introduction à la théorie des sous-ensembles flous. Paris: Masson; 1975. Vol. 3.

Cox E. The fuzzy systems handbook. New York: Academic; 1994.

Kundu S. The min-max composition rule and its superiority over the usual max-min composition rule. Fuzzy Sets Sys. 1998;93:319-29.

Lambert-Torres G, Pereira Pinto JO, Borges da Silva LE. Minmax techniques. In: Wiley encyclopedia of electrical and electronics engineering. New York: Wiley; 1999.

Shannon CE. A mathematical theory of communication: Part I, discrete noiseless systems. Bell Syst Tech J. 1948;27:379-423.

Shannon CE. A mathematical theory of communication: Part II, the discrete channel with noise. Bell Syst Tech J. 1948;27:623-56.

White H. Neural network learning and statistics. AI Expert. 1989;4(12):48-52.

Kullback S. Information theory and statistics. New York: Wiley; 1959.

Iordache O, Corriou JP, Garrido-Sánchez L, Fonteix C, Tondeur D. Neural network frames. application to biochemical kinetic diagnosis. Comput Chem Eng. 1993;17:1101-13.

Iordache O. Modeling multi‑level systems. Berlin: Springer; 2011.

Tryon RC. A multivariate analysis of the risk of coronary heart disease in Framingham. J Chronic Dis. 1939;20:511-24.

Jarvis RA, Patrick EA. Clustering using a similarity measure based on shared nearest neighbors. IEEE Trans Comput. 1973;C22:1025-34.

Page RDM. Program TreeView. Glasgow (UK): Universiy of Glasgow; 2000.

Huson DH. SplitsTree: Analizing and visualizing evolutionary data. Bioinformatics. 1998;14:68-73.

Hotelling H. Analysis of a complex of statistical variables into principal components. J Educ Psychol. 1933;24:417-41.

Kramer R. Chemometric techniques for quantitative analysis. New York: Marcel Dekker; 1998.

Patra SK, Mandal AK, Pal MK. State of aggregation of bilirubin in aqueous solution: Principal component analysis approach. J Photochem Photobiol Sect A. 1999;122:23-31.

Jolliffe IT. Principal component analysis. New York: Springer; 2002.

Xu J, Hagler A. Chemoinformatics and drug discovery. Molecules, 2002;7:566-600.

Shaw PJA. Multivariate statistics for the environmental sciences. New York: Hodder-Arnold; 2003.

Kloucek P, Smid J, Flesar J, Havlik J, Titera D, Rada V, Drabek O, Kokoska L. In vitro inhibitory activity of essential oil vapors against Ascophaera apis. Nat Prod Commun. 2012;7:253-6.